| Yordan Alvarez, HOU | 1-3, HR, R, 2 RBI |
| Kyle Tucker, HOU | 1-4, HR, R, RBI |
| Jeremy Peña, HOU | 2-3, 2 R, 2B |
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | R | H | E | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| #5 Mariners | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 2 | 5 | 0 |
| #1 Astros | 0 | 1 | 0 | 0 | 0 | 2 | 0 | 1 | x | 4 | 6 | 1 |
| W: Héctor Neris (1-0) S: Ryan Pressly (1) | ||||||||||||
| L: Luis Castillo (1-1) | ||||||||||||
|
MLB Postseason 2022 –
American League Division Series Best of Five, Game 2 Astros lead series 2-0 |
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| Minute Maid Park – Houston, Texas | ||||||||||||
| Box Score | ||||||||||||